Heterochromia Treatment with laser – Causes of Heterochromia
Have you ever seen a person with eyes of varying colors? There are very few individuals like this in the world. This condition is referred to as heterochromia. What is heterochromia? Heterochromia is the presence of different colors in anatomy. It is typically found in the iris, but can occasionally be observed in the hair and skin. Heterochromia is caused by a melanin deficiency or excess (pigment). This could be a result of genetic mosaicism, chimerism, disease, or trauma. The quantity of melanin in the iris determines whether our eyes are blue, green, brown, or hazel. While brown eyes contain the most melanin, blue eyes contain the least in iris. After the first successful laser treatment of heterochromia by Dr.Mete in the world, cosmetic eye color change treatments started today.
heterochromia is a treatable anomaly
We can say that “heterochromia” results from different excess or deficiency concentrations in the distribution of melanin. Contrary to popular belief, heterochromia does not impair vision because it is not a disease and poses no threat to our health unless it increases significantly. Although you do not necessarily need to be treated for heterochromia, if it affects your psychological state, we can successfully solve your problem with the laser method. There are exceptions to this. For example, if a tumor or a subsequent disease (such as pigment dispersion syndrome, etc.) has developed, this condition must be treated.

The amount of melanin pigment in the iris, which gives the eye its color, determines how light or dark the eye is.
Heterochromia is observed in both humans and animals. To put it another way, the darker the eye, the higher the concentration of melanin pigment, and the lighter the eye, the lower the concentration. Even though we do not fully comprehend the cause of Hereditary Heterochromia iridis, it would not be surprising if it were caused by mutations in the genes that regulate the distribution of melanin pigment in the iris. Heterochromia is a form of color variation. The term is typically used to describe variations in the color of the iris, but it can also be applied to hair and skin. The production, distribution, and concentration of melanin determine heterochromia (a pigment). This condition is known as heterochromia iridum or heterochromia iridis.
The iris color of mammals, including the human iris, is highly variable. However, only eumelanin and pheomelanin pigments are present. Eye color is determined by the total amount of these pigments, their relationship to one another, how they are distributed in the stromal layers of the iris, and how light scatters.
Heterochromia is primarily classified by its onset, either genetic or acquired.
Although a distinction is often made between heterochromia that affects the eye completely or only partially (sectoral heterochromia), it is frequently classified as genetic (due to mosaicism or congenital) or acquired, with the iris being darker or lighter and an indication of the affected iris or part of the eye. The majority of cases of heterochromia are caused by genetic factors such as chimerism or are inherited from a parent. Some of these cases are benign and devoid of pathology, while others are associated with diseases and syndromes. Sometimes, a change in eye color can result from illness or injury.
Heterochromia, or H. iridium is a condition of discoloration between the eyes-heterochromia treatment
It can be sporadic or benign, but can also be an indication of an eye disease. An abnormal iris can be congenital or acquired. Some diseases such as Horner’s syndrome, Fuchs heterochromic iridocyclitis, and oculodermal can cause it.Heterochromia refers to a color variation that can be seen in the eyes, but also in the hair and skin. The over- or under-distribution of melanin pigment, which is involved in all types of colour in the body, causes it. A mutation in the autosomal chromosomes, generally on the 8th chromosome, is the cause of this regional variation.It’s interesting to see that some people come to us for heterochromia therapy, while others apply to have heterochromia produced in their eyes by a laser.
Dr. Mustafa Mete, who treated heterochromia for the first time in the world, claims that the new procedure increases the chances of success. Laser Heterochromia Treatment can be applied quite easily. We fixed many heterochromia cases by using lumineyes laser eye color change therapy.
what is heterochromia?
It is a rare case in which the colors of the eyes are completely different. The term “heterochromia” is derived from the Greek. The word “hetero” refers to something completely different, while “chroma” refers to this color.
It is mostly seen in animals such as dogs and cats. However, it is also sometimes found in humans. It is also called “Heterochromia iridium” or “Heterochromia iridis”. This is caused by differences in the distribution and concentration of animal pigment. Melanin pigment is the pigment that gives color to your eyes, hair, and skin.
Also, heterochromia has completely different causes and various forms.
Causes of Heterochromia
Heterochromia may be attributed to melanocytosis, Waardenburg syndrome, unilateral topical use of prostaglandins, and siderosis may be an etiological factor. The most common explanation for this situation is that it is innate, a result of genetics. This is usually the result of a benign mutation affecting the melanin pigment event in the iris. In a very detailed analysis, it was mentioned that central heterochromia would occur at birth. This will happen to anyone, whether they have a family history of heterochromia or not. It mostly has no effect on net controlling power and is not caused by any discomfort. In such cases, the condition does not need any diagnosis or treatment.

In addition, this condition will develop even as a result of an injury, illness, or medication. It is known as non-hereditary heterochromia.
A famous celebrity with non-hereditary heterochromia is David Pioneer. It is usually caused by the following diseases:
- Eye Surgery
- Iris Ectropion syndrome
- Eye injury
- Diabetes
- Glaucoma
- Posner-Schlossman syndrome
- Iris tumor
- Pigment Dispersion Syndrome
Abnormal iris darkness
Deposition of substance
Siderosis is the deposition of iron in the ocular tissues caused by a penetrating injury and a retained intraocular foreign body containing iron.
Hemosiderosis can be caused by prolonged hyphema (blood in the anterior chamber) as a result of ocular trauma.
Prostaglandin analogue eye drops (latanoprost, isopropyl unoprostone, travoprost, and bimatoprost) are applied topically to glaucoma patients to reduce intraocular pressure. Some individuals who have taken these medications have developed concentric heterochromia. The stroma surrounding the iris sphincter muscle darkens relative to the periphery. It is assumed that iris melanocytes stimulate melanin synthesis.
Nevus-like neoplasms and melanomatous tumors.
Syndrome endothelial iridocorneal
Fuchs heterochromic iridocyclitis is characterized by low-grade, asymptomatic uveitis in which the iris of the affected eye becomes hypochromic and pale, resembling moth damage. Heterochromia can be quite subtle, particularly in patients with lighter iris pigmentation. It is typically most visible during the day. Several studies have attempted to determine the frequency of Fuchs-related heterochromia. The results indicate that people with dark eyes are less likely to notice iris color changes.
Acquired Horner’s syndrome is typically acquired, like neuroblastoma, but is occasionally inherited.
Additionally, neoplasm-melanomas may be very lightly pigmented, and a lighter-colored iris may be a rare indicator of metastatic disease to the eye.
resulting from tissue loss
Heterochromia has also been observed in Duane syndrome patients.
Chronic keratoconjunctivitis
Juvenile xanthogranuloma
Lymphoma and leukemia
How Do We Change Eye Color in people with heterochromia? Heterochromia Treatment with laser
As we mentioned before, eye color change is achieved by using only laser in our clinic. Because this is the safest and most effective way. With the unique effectiveness of the “8G laser” and the experience of Dr.Mete, we can successfully change eye color. Heterochromia treatment with laser is very easy and has a high success rate.
Only Mylumineyes clinic in the worldwide offers Heterochromia Treatment with Laser.
Types of Heterochromia
While there are alternative variations, most people are generally classified as having 3 types of heterochromia.
Central Heterochromia
It is a typical type of heterochromia. These people have completely different colors in the corners of their eyes. Near the corners of the pupils, there is a golden hue, and the rest of the iris is a special color.
Complete Heterochromia
In this type of situation, people have completely different colored eyes. For example, one eye may be brown-hazel and the other blue.

Sectoral or Segmental Heterochromia
Another type of heterochromia is segmental. In this case, a larger part of the iris is affected. This will develop in each eye, or exactly one eye. An irregular spot on the iris is referred to as sectoral heterochromia.It does not form a circle around the iris.